Nearly the whole of my research career took place in the present ‘golden age’ for the study of DNA, genes and genomes. At the end of the 1960s scientists had indicated how useful it would be to be able to isolate individual genes in order to study their structure and function. That wish was fulfilled in the spin-offs from the invention in the early 1970s, of genetic modification (genetic engineering), a scientific milestone that marked the start of this golden age.
By the end of the 20thcentury experiments were being done, that thirty years earlier were not even dreamed of. This was certainly true in my research group’s work on the biochemistry and genetics of DNA replication, giving us the real privilege of uncovering some of the beautifully complex and intricate mechanisms used by cells in ‘managing’ and copying their genetic material. Continue reading →
It’s obvious that our own planet is friendly to life, but what about the rest of the universe? Is the rest of space too cold and dark – or hot – to allow life to develop? Was the development of life on earth a hugely improbably event, or pretty much a forgone conclusion? The Nobel Prize-winning biochemist Christian de Duve spent the last few years of his career investigating this question, and came up with a surprising answer. In this post I’ll share five of the characteristics of life that he studied. Continue reading →
Children are delighted by living things that most adults think are icky or mundane. Last spring my daughter Lucy, now age 6, found a large earthworm and named it Cinderella. She played with it for hours. Not a week later my son Josiah, 4, caught a big brown toad in our backyard and squealed repeatedly, “He’s adorable!” (Not everyone would pick that adjective, but I agreed.) They fixate on the fish tank at the dentist’s office or our family’s ant farm, taking in every detail and pestering me with a steady stream of questions.
Some of the questions they ask are profound. We were almost to school the other day when Lucy asked, “Is there any number bigger than infinity?” and then, “Is God bigger than infinity?” I paused, breathless with parental joy, before I responded. Continue reading →
I am an ex-cell biologist. Whilst I was a PhD student, it felt like cells were involved in every aspect of my life. I would grow cells, study cells, read about cells, spin them in centrifuges, look at them down a microscope, and visit them at 2am to take timepoints for particularly gruelling experiments. When I spoke to my relatives, the question ‘How are you?’ was often followed by: ‘How are your cells behaving?’. Continue reading →
As a molecular biologist, I spent about spent 20 years in lab-based research. Much of this was working on leprosy, which took me to all kinds of fascinating places, including Ethiopia, India- and almost a decade in Nepal. I now work full time for the Church of Scotland Society, Religion and Technology (SRT) Project (www.srtp.org.uk), which aims to help the church to engage with ethical issues in science. Continue reading →
I recently heard a new metaphor for the gene. Although this phrase was coined by a physicist*, I think it’s an interesting one. The concept of ‘The Eager Gene’ comes from Andrew Steane, Professor of Physics at Oxford University, in his book Faithful to Science (see previous blog).
Steane writes that “Genes are, of course, inanimate molecules, having no eagerness or moral capacity, but Continue reading →