Interview: Purpose and Pleasure – Exploring Addiction Science

FreeImages.com/Dean Smith
FreeImages.com/Dean Smith

What is the interface between ideas of purpose of science, and in faith – or life in general? This was one of the main topics of conversation during my interview with Alan Gijsbers. I wanted to find out whether medical professionals have a similar sense of wonder or spirituality to some laboratory scientists. Although the challenges are very different in medicine, I found that Alan shared the same combination of curiosity, questioning, and connection with deeper issues that is so important for many other researchers.

Dr Alan Gijsbers
Dr Alan Gijsbers

What do you do?

I’m a physician in addiction medicine, which means I deal with people who have got a problem with alcohol and/or other drugs. I work at the Royal Melbourne Hospital in Australia, where I also teach medical students. In all our conversations I try to create a seamless interface between our different faith commitments and the people we see.

So this is a Christian hospital?

No, but my view of secularity is very much affected by my life in India, where I spent five years at the Christian Medical College and Hospital in Vellore. It’s an explicitly Christian hospital, but catering largely for people with all sorts of faith – in particular, Hindu of course. In India your faith commitment is part of what you deal with in the marketplace. So the Muslim will be recognised as a Muslim, the Hindu will be recognised as a Hindu, and a Christian will be recognised as a Christian, and there will be a free discussion between these faith commitments. That is a very different form of secularisation from what happens in the West, where “secularisation” means that faith is subtracted from the world of human interactions. I recently discussed with a younger doctor the possibility of taking a spiritual history, finding out what the patient’s faith commitments were, and in that way, using those faith commitments as a way of helping the person to understand who they are and where they’re going. It’s quite a well-recognised practice. It’s important that as Medical Director of the Addiction Medicine Service, I create an environment where people are free to explore their spirituality.

Does anything that you’ve come across give you a sense of awe?

There’s always a sense of awe, I think, just as we are “fearfully and wonderfully made’”. If we are talking about basic neuroscience, of course the outstanding question is “What is human?” or “Who am I?” Anybody who thinks there’s a drug solution to a drug problem doesn’t understand the drug problem, because it’s actually a problem of human beings in distress, and therefore it has to be dealt with at the human level, which is the level of narrative. Human beings cannot be simply reduced down to their biochemical parts.

You are looking at scientific factors, but presumably you are looking at lots of other factors as well?

You’ve got to tailor your scientific approaches according to the subject at hand. Clinical medicine is an amalgamation of a number of different sciences, including anatomy, physiology, biochemistry and pathology, but it is also the science of the intact human being. The challenging area right now is psychiatry, because the manual by which all psychiatrists seem to define illnesses is purely phenomenological – describing things as they are – but science will always ask why, and start to develop theories. We’re starting to do this in addictions. We’re defining what an addition is, and starting to understand the biology of the limbic system. We’re also throwing in the question of purpose. Why’s the limbic system there? Why did it evolve that way?

FreeImages.com/Shirley B
FreeImages.com/Shirley B

Humans are built for pleasure, as are animals. So what is the purpose of pleasure? What is it useful for? I argue that the purpose of pleasure is to create social bonding – to make social relationships – so we’re starting to understand addiction as a disease of relationships. These are hypotheses we’re putting forward, and let’s see if we can test these to develop a better science of addiction.

In biology, to ask questions about purpose is quite controversial.

Asking the question, “What is the evolutionary advantage?” is easy, but we human beings still have to ask the broader teleological question, which is “What is the purpose of my life? What am I here for?”

Questions of meaning and purpose are lurking in the wings for anybody who has an addiction. Why am I pursuing these drugs to the detriment of everything else? Patients are asking questions of meaning and purpose all the time, so I would encourage them to pursue them!

FreeImages.com/Bas van der Pluym
FreeImages.com/Bas van der Pluym

It sounds from what you are saying that you can’t separate the spiritual from the physical

I would go further and say the problem is that underlying our discussion is still the Enlightenment assumption of autonomous individualism, when in fact we are socially connected human beings and relationships are really fundamental to who we are. If that’s the case, connectedness becomes an important issue. The only comfort some of my patients have is a very second rate form of pleasure, which is drugs and alcohol, because they have no social connectedness.

What do your colleagues think about your point of view?

The last paper I read in our journal club was the John Templeton series on “Does moral action depend on reasoning?”, because this raises the question of “How do people decide to do something?” So there’s been an interesting discussion along those lines. I also invited George Ellis, who is a professor of mathematical sciences, to give a lecture at the Royal Medical Hospital on emergent complexities [the whole is more than the sum of the parts]. I think it must be the only time a physicist has talked to physicians on this. I thought this was an important concept for physicians to grasp in terms of the new field of neuroethics, “Did my neurons make me do it?”

Is there anything else in your work that gives you a feeling of awe or wonder?

One of the great things is a simple conversation that I’ve had numerous times with different friends, about Ernest Rutherford‘s famous quote, “There are two forms of science: physics and stamp collecting”…

…he was being rude about stamp collecting, wasn’t he?

Yes, but I don’t mind because the best stamp collecting was Mendelev’s classification of the elements, which turned into the periodic table, which turned into the structure of the atom! I’ve just finished Stephen Jay Gould’s book The Hedgehog, the Fox and the Magister’s Pox, where he points out that it’s all very well to collect things, but it’s the way you arrange them which gives meaning. Of course the genius of Charles Darwin was to arrange them from simplest to most complex, and then to see the links between them. So Rutherford might have been tongue-in-cheek or rude, but I’m a clinician. I classify all the time, and when those classifications are ordered, you’ll see patterns emerging which are helpful.

So although Rutherford was trying to write some things off as stamp collecting, you just say “No, I like stamp-collecting!”

Exactly!

9 thoughts on “Interview: Purpose and Pleasure – Exploring Addiction Science

  1. David Thomson September 3, 2015 / 11:00 am

    Reblogged this on Bishop's Blog and commented:
    This is a really interesting interview. Look out for sensible thinking on sorts of secularism, sense of purpose and the new subject of neuroethics.

    Like

  2. Clare Redfern September 3, 2015 / 2:29 pm

    Hi Ruth,
    “he was being rude about stamp collecting, wasn’t he?”

    Don’t you mean he was being rude about biology?

    But a small quibble, it’s a great post. Big ideas!

    Like

    • Ruth M. Bancewicz September 3, 2015 / 3:46 pm

      I guess so! Ah well, at least we can appreciate how exciting biology is…

      Like

  3. thebookofworks September 3, 2015 / 3:48 pm

    Great interview, and some compelling statements from Dr. Gijsbers. My view of the Rutherford quote is that it is an. exaggerated truth. One of my pet peeves (currently being explored on my blog) is the stamp collecting nature of molecular biology. In other words, I suffer from physics envy..

    Like

    • Alan Gijsbers September 4, 2015 / 12:04 am

      One of my aha moments was the observation (by Karl Barth, but I’m sure others would also make it) that the subject of the science determines the methodology of the science. Hence while measurement and maths are important in physics they may be inappropriate in a descriptive science like anatomy or in the complex analysis of what goes on in a doctor-patient relationship. We need to work in our area according to the lights in that area.

      Like

  4. Dennis Read September 4, 2015 / 8:48 pm

    Very interesting interview with a scientist working in the animate (human)world.I found many of the comments I was able to relate to my professional inanimate world,dealing with inorganic chemicals.for example the periodic table and atomic structures.Plenty of explanations for the What and the How,but the great unknown is the Why.Was such an ordered system completely random? The question behind it is the Who!. Lots of food for talks when leading worship.

    Like

  5. Richard Hosking September 8, 2015 / 8:33 am

    Hi Ruth, Great stuff from Alan!

    Interesting point about addiction, social connectedness and human distress. Physician Gabor Mate also believes we are not discrete, individual entities. He looked after drug addicts in downtown Vancouver, and was struck by the frequent history of childhood abuse, particularly among female users.*

    He thinks the neurobiological effect of hard drugs on already dysregulated limbic systems in the context of chaotic social lives, makes addictive substances like cocaine very difficult to give up.

    It was fascinating to hear Rachel Yehuda discuss the effects of physiological and psychological stress on developmental biology, and the transgenerational epigenetic changes in children of Holocaust survivors.* Gabor himself was born in Budapest in 1944 and was just 2 months old when the Nazis invaded. He attributes his own psychological vulnerability to the enormous difficulties his mother faced in the Jewish Ghetto during that time.*

    However, it’s great that Rachel’s work suggests some of these epigenetic changes that affect the physiological stress response may be altered by psychotherapy.* I wondered if anyone’s looked at this in people recovering from substance misuse?

    Incidentally, Rutherford might have enjoyed physicist Jim Al-Khalili’s new book about biology.* The strange world of quantum physics appears to be fundamental to photosynthesis, olfaction, metamorphosis, migration, and possibly genetic mutation and evolution itself.*

    Quantum biology has arrived!

    ——-

    G.Mate ‘In the Realm of Hungry Ghosts: Close Encounters with Addiction’ (Random House Canada 2013)
    https://en.wikipedia.org/wiki/Gabor_Mat%C3%A9_(physician)
    http://m.democracynow.org/stories/11900

    http://www.onbeing.org/program/rachel-yehuda-how-trauma-and-resilience-cross-generations/7786
    Yehuda R et al. Epigenetic Biomarkers as Predictors and Correlates of Symptom Improvement Following Psychotherapy in Combat Veterans with PTSD. Frontiers in Psychiatry. 2013;4:118. doi:10.3389/fpsyt.2013.00118

    J. Al-Khalili, J. McFadden ‘Life on the Edge: The Coming of Age of Quantum Biology’ (Bantam Press 2014)
    BBC 4 ‘The Secrets of Quantum Physics: Episode 2 Let There Be Life’
    Available in the UK for the next 18 days
    http://www.bbc.co.uk/programmes/b04v85cj

    Like

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